COURSES
Cancer Biology & Therapy
The Global Cancer Consortium offers a comprehensive graduate (Masters and Doctoral degree) level 3-credit hour course in two parts:
(Part 1) Basic Cancer Biology
The objective is to provide students with a comprehensive understanding of cancer biology.
(Part 2) Translational Oncology and Epidemiology
The objective is to introduce students to therapeutic approaches in clinical oncology involving both conventional and experimental strategies, and also epidemiology.
There are no fees for the course but registration is mandatory.
COURSE DESCRIPTION
This is an advanced level course for PhD, MD/MS/DM/MCh, PharmD, MPharm, MSc, MTech students, postdoctoral trainees, and faculty.
This comprehensive biology and therapy of cancer course includes lectures on the fundamental mechanisms of cancer development and key features of cancer therapies. The lectures are presented by basic/translational science and clinical faculty.
TOPICS COVERED:
Cancer Epidemiology
Carcinogenesis
Pathogenesis
Angiogenesis
Tumor-stromal Interactions
Invasion and Metastasis
Defective Cell Cycle Regulation and Signaling Pathways in Cancer
Cancer Stem Cells
Cancer Genomes
Cancer Epigenetics
Experimental Systems Including Animal Models and Tumor Imaging
Diagnostic and therapeutic approaches in clinical oncology involving both conventional and experimental strategies are covered. In addition, lectures include assays, methods, instrumentation, biostatistics and bioinformatics that are relevant to cancer.
Curriculum Overview
PART ONE:
Basic Cancer Biology
1. Oncogenes and Tumor Suppressor Genes
2. Cell Cycle in Cancer
3. Genome Instability in Cancer Development: David Orren and Zhigang Wang
4. Gene Mutations and Cancer Genomes
5. Chemical Carcinogenesis
6. Cancer Epigenetics I
7. Cancer Epigenetics II
8. Telomeres, Telomerase, and Cell Immortalization in Cancer-1
9. Telomeres, Telomerase, Cell Immortalization and Aging-2
10. Senescence, Aging and Cancer
11. Cancer Cell Death (apoptosis, autophagy, ferroptosis, necroptosis)
12. Role of viruses in cancer-1
PART TWO:
Clinical Translational Oncology, Models, Technology, Biostatistics and Cancer Epidemiology
25. Cancer Methods and Resources
26. Animal Models in Cancer Research I
27. Animal Models in Cancer Research II
28. Tumor Tissue Collection and Analysis
29. Liquid Biopsies in Cancer
30. DNA Damage and Genome Instability Techniques
31. Cancer Informatics: Database Navigation
32. Pharmaco-Genomics and Pharmaco-Proteomics of Cancer
33. Pathologist’s View of Cancer I
34. Pathologist’s View of Cancer II
35. Tumor Immunology I
13. Role of viruses in cancer-2
14. Cancer Stem Cells
15. Signal Transduction Pathways in Cancer I
16. Signal Transduction Pathways in Cancer II
17. Signal Transduction Pathways in Cancer III: Role of PTMs
18. Role of Hormones in Development/Progression of Certain Cancers: Dr Fong
19. Hematopoiesis and Liquid Cancers
20. Tumor-Host Stromal Interactions and Metastasis I
21. Tumor-Host Stromal Interactions and Metastasis II
22. Angiogenesis in Cancer
23. Tumor Microenvironment I
24. Tumor Microenvironment II
36. Tumor Immunology II
37. Surgical Oncology
38. Radiation Therapy I
39. Radiation Therapy II
40. Cancer Chemotherapy
41. Precision Oncology I
42. Precision Oncology II
43. Cancer Epidemiology I
44. Cancer Epidemiology II
45. Cancer Informatics Patient Registry
46. Cancer Biostatistics
COURSE GRADING OPTIONS
Students can choose the course Part 1 and/or Part 2 for either Credit or Audit.
CREDIT COURSE
Students will be evaluated on the basis of the written examination(s) and provided a Certificate of Completion. There will be at least one closed-book exam. Each exam will last two hours with 100 questions. The grading standards employed are listed below.
A: 90-100%
B: 80-89%
C: 70-79%
D: 69% and below
AUDIT COURSE
Students can attend, refresh their knowledge base and scientific advances without requiring the tests.
Ready To Apply?
Enrollment process for prospective Cardio-Oncology trainees:
• Submit the contact form and your CV to Dr. Stephen Casselli, Executive Director, IC-OS
• Fill out an application form provided by Dr. Casselli.
After careful review, the applications will be approved if they meet the eligibility criteria for one of the two tracks mentioned above. Only those applicants who are approved for enrollment in the course will pay their Fees directly to IC-OS for the IC-OS Certification Exams before gaining access to the online lectures.
Instructions for payment of fees will be provided by Dr. Stephen Casselli.
Course Copyright
The lectures are delivered online and remain the intellectual property of the faculty member who delivered them. Access is provided only to those who register for the course. Individuals enrolled in the course may use the original content for their learning and completion of course requirements. Course recordings may not be reproduced, shared with anyone, or uploaded to other online environments. Trainees are not permitted to re-record the video and audio recordings of the course material. Downloading, copying, photographing or distributing them is prohibited. Trainees registered for the course are expected to maintain the security of their internet accounts used to access the recorded course materials.